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The fonds shows W. G. Henry's activities as a medical student at the Toronto School of Medicine and then at the Faculty of Medicine, McGill University, from 1878-1883. The material consists of 18 printed cards made out in writing to W. G. Henry: 6 from the Toronto School of Medicine for the sessions 1878-79 and 1879-80 (1 proof of registration/lecture programme card, 5 admission tickets); 6 from the University of McGill College or Faculty of Medicine, 1880-1882 (4 admission tickets, a certification card, an initialed dissection examination card); 5 certification cards from the Montreal General Hospital, 1881-1883; an admission tickets for the "University Dispensary" (undated).

Fonds contains the admission cards of William Forrest for the Montreal Medical Institution Library, the Montreal General Hospital and the lecture of Anatomia Physiologia et Chirurgica of John Stephenson, in 1824-1825. The fonds includes three admission cards.

The fonds documents William B. Howell's poetry. The fonds contains a bound typescript of poems with two drawings by W.W. Francis.

The fonds contains two significant bodies of material representing the life of William B. Malloch. The original accession documents Malloch's life as a medical student at McGill and the links he kept with his alma mater, 1863-1870. These materials include admission cards, programmes, certificates, examination copies, newspaper clippings and an indenture of apprenticeship. The second body of contains medical instruments and documents from Malloch's professional life. A number of Indigenous artifacts collected by Malloch while travelling in the Artic regions of Canada were transferred to the McCord Museum (2024).

The fonds contains letters, 1948-1958, to and from Dr. W.W. Francis. It also includes two poems by Francis, and a letter from the Dean of the Faculty of Medicine regarding death of Francis in 1959.

The fonds contains two sketchbooks of coloured sketches and shows William Arthur Johnson's activities in natural sciences and microscope work.

Fonds contains the letters of certification of William A. De Wolf Smith's attendance at medical courses at McGill University in 1883. The fonds includes three letters of certification signed by teachers.

The Penfield fonds consists of over eighty metres of Penfield's personal and professional records dating from his childhood up until his death in 1976, including during his career at the Montreal Neurological Institute. The materials in the fonds include photographs, correspondence, manuscripts and drafts of publications and speeches, research notes, glass slides, bound reports, films, and academic gowns.

The fonds includes a copy of No. 3 Canadian General Hospital (McGill), 1914-1919 owned by Walter de M. Scriver and ephemera relating to Canadian General Hospital No. 3. It also contains a handwritten poem entitled "Tune of T'anks," composed by Scriver for his family and dated France, 1915.