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Fonds consists principally of one three-ring loose leaf holograph notebook written in pencil and ink. The notebook details cases that Morton worked on during the period of February to May, 1935, while at Guy’s Hospital in London. Fonds also includes a letter from real estate broker William E. Speed to Capt. W. B. Holms concerning a property rented to the Mortons; single blank leaf with letterhead of C. S. Morton (Harry Stafford Morton’s father); New Year’s card from Earle C. Phinney; and newspaper clipping of editorial by Sir William Osler, “Promethean Gift of the Century Physical Suffering Diminished.”

The fonds contains original and typescript letters, manuscript notes, newspaper clippings, journal extracts, reminiscences and more, assembled by Harvey Cushing chiefly between 1920 and 1924 during the course of his research for the biography of William Osler. For the biography, Cushing collected and retyped over 7500 pieces of Osler's correspondence, among which are some original letters.

The fonds is separated into three series: Manuscripts, Working Notes and Osler's Correspondence. It also contains photographs, annual reports, publications, clippings, one watercolor painting, one postcard. Osler's correspondence is further arranged in three subseries based chronologically.

Fonds shows Henry Beaumont Small's activities as a medical student through his admission cards for his complete medical formation. It contains 43 admission cards signed by or printed for the teachers, among them William Osler.

Collection contains a manuscript letter from Henry Lyman to his wife, Mary, in Granby; dated July 25, 1849, when the druggist shop Wm. Lyman & Co. was located at 194 and 196 St. Paul St. in Montreal, the letter deals principally with the cholera epidemic in the city.

Fonds documents the Montreal years of H.V. Ogden and the ties he had with Sir William Osler. The fonds contains the correspondence of H.V. Ogden consisting of letters from May Francis and Marian Francis (Osborne), letters from George Cantlie, a letter from Dr. Robert Palmer Howard and a letter from Edmund J.A. Rogers.

Fonds shows Herbert Frederick Moseley's relations with his editor for his book "Shoulder Lesions". It contains an original manuscript with the publisher's annotations for the 1945 edition and another complete copy.

The collection consists of documents pertaining to Dr. H. S. Birkett's medical activities, including 117 bound volumes of patient records (1889-1942), medical notebooks (1893-1896), bound RVH reports (1894-1938), RVH charts (1901-1920) and registers (1899-1917). There are also various letters addressed to Mr. and Mrs. Birkett, a manuscript, newspaper clippings, various degrees and medical association certificates, as well as photographs of H. S. Birkett's personal life and professional life at McGill and elsewhere. The collection also includes various artifacts collected by H. S. B, including military and medical memorabilia collected by H. S. Birkett.

Fonds documents H.R. Clouston's medical activities and his association with McGill University. The fonds contains notes, reprints, photographs and newspapers clippings.

Fonds documents Dr. H.E. MacDermot's medical-historical activities. The fonds contains newspaper clippings, manuscript notes, photographs, lectures notes, and a draft of The MGH, the Years of Change.

The collection contains W.W. Francis memorabilia: an obituary notice, reprints with notes from W.W. Francis to Miss Anderson, a copy of a photograph of Francis with Osler, a program of an annual meeting of the Medical Library Association and a letter from Francis to Miss Anderson.